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Lonart DS Tab ACT 80/480 (arthemeter/lumafantrin)

3,000.00

Lonart DS is an anti-malaria medication composed of Artemether and Lumefantrine. It is used to treat acute, uncomplicated infections due to Plasmodium falciparum or mixed infections including P. falciparum. This combination is effective against both drug-sensitive and drug-resistant P. falciparum, making it recommended for malaria infections acquired in areas where the parasites may be resistant to other antimalarials.

Lonart DS is an anti-malaria medication composed of Artemether and Lumefantrine. It is used to treat acute, uncomplicated infections due to Plasmodium falciparum or mixed infections including P. falciparum. This combination is effective against both drug-sensitive and drug-resistant P. falciparum, making it recommended for malaria infections acquired in areas where the parasites may be resistant to other antimalarials.

Artemether and Lumefantrine work by interfering with the conversion of haem, a toxic intermediate produced during haemoglobin breakdown, to the non-toxic haemozoin (malaria pigment). Lumefantrine is thought to interfere with the polymerisation process, while Artemether generates reactive metabolites as a result of the interaction between its peroxide bridge and haem iron. Both Artemether and Lumefantrine have a secondary action involving inhibition of nucleic acid and protein synthesis within the malarial parasite.

Lonart DS is also recommended as a standby emergency treatment for travelers to areas where the parasite is resistant to other drugs. It is used in patients weighing 5 kg (11 lb) and above.

Please note that Lonart DS is a prescription medicine and should be used under the supervision of a healthcare professional. Always follow the dosage instructions provided by your healthcare provider.

Possible side effects of Lonart DS include low appetite, vomiting, stomach pain, nausea, diarrhoea, headache, dizziness, sleeplessness, tingling or pricking sensation, unusual muscle movements, joint pain, fatigue, pounding and irregular heartbeat, skin disorders like rashes or itching, difficulty in walking properly, lack of energy, and cough.

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